The funding information was inadvertently omitted from the published online version of the manuscript. The Acknowledgements section should read: This work was supported by a grant-in-aid from the Heart and Stroke foundation of Ontario to JP (#T6748). GC was supported by a Research Training award from the Hospital for Sick Children. The authors wish to thank Dr. James Wasmuth and Tuan On for their assistance in compiling data for the phylogenetic profiles.