Gene Details


gene name: moaD


locus tag k12ECK0773 Crenarchaeota Euryarchaeota Nanoarcheota Alphaproteobacteria Betaproteobacteria Gammaproteobacteria Deltaproteobacteria Epsilonproteobacteria Cyanobacteria Actinobacteridae Firmicutes Spirochaetes others Protist Microsporidia Fungi Metazoa Plantae
information on phylogenetic profile
locus tag mg1655b0784
locus tag w3110JW0767
gene name k12moaD
locus namemoaD
synonyms of locus namechlM, chlA4

scop id54285
superfamilyMoaD/ThiS
pfam idPF02597
pfam domainThiS family
tigrfam idTIGR01682
namemoaD
functionmolybdopterin converting factor, subun

swissprot nameMOAD_ECOLI
descriptionMolybdopterin-converting factor subunit 1 (MPT synthase subunit 1)|(Molybdopterin synthase subunit 1) (Molybdenum cofactor biosynthesis|protein D) (Molybdopterin-converting factor small subunit).
seq length81
fastaseq

go idGO:0006777
go termMo-molybdopterin cofactor biosynthesis

gene product descriptionmolybdopterin synthase, small subunit
comment gene product description
evidenceE
context
gene product descEnzyme
cell locationCytoplasmic
featuresCDS

functional category codeH
functional categoryCoenzyme transport and metabolism

reference #1Biogenesis of molybdenum cofactors.

Hinton S., Dean D. (Crit Rev Microbiol. 1990; 17(3):169-88)
reference #2The pterin molybdenum cofactors.

Rajagopalan K., Johnson J. (J Biol Chem. 1992 May 25; 267(15):10199-202)
reference #3The biosynthesis of molybdopterin in Escherichia coli. Purification and characterization of the converting factor.

Pitterle D., Rajagopalan K. (J Biol Chem. 1993 Jun 25; 268(18):13499-505)
reference #4Molecular genetic analysis of the moa operon of Escherichia coli K-12 required for molybdenum cofactor biosynthesis.

Rivers S., McNairn E., Blasco F., Giordano G., Boxer D. (Mol Microbiol. 1993 Jun; 8(6):1071-81)
reference #5Structural studies of molybdopterin synthase provide insights into its catalytic mechanism.

Rudolph M., Wuebbens M., Turque O., Rajagopalan K., Schindelin H. (J Biol Chem. 2003 Apr 18; 278(16):14514-22)
reference #6Crystal structure of molybdopterin synthase and its evolutionary relationship to ubiquitin activation.

Rudolph M., Wuebbens M., Rajagopalan K., Schindelin H. (Nat Struct Biol. 2001 Jan; 8(1):42-6)

phylogenetic profile
 
1 1 1 1 1 1 1 1 1 1 1 1 1 50 1 1 1 1 1 1
1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 50 1 1 53 54
54 1 1 51 1 1 1 1 1 52 52 52 56 56 64 1 1 1 64 1
1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
1 1 1 1 1 1 1 113 156 161 161 109 1 1 111 52 107 109 70 73
82 141 143 141 90 160 160 110 100 114 1 1 1 1 1 121 121 121 1 1
1 1 1 1 1 1 1 1 1 1 1 1 1 1 58 1 1 1 1 1
1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1