Gene Details


gene name: mcrA


locus tag k12ECK1145 Crenarchaeota Euryarchaeota Nanoarcheota Alphaproteobacteria Betaproteobacteria Gammaproteobacteria Deltaproteobacteria Epsilonproteobacteria Cyanobacteria Actinobacteridae Firmicutes Spirochaetes others Protist Microsporidia Fungi Metazoa Plantae
information on phylogenetic profile
locus tag mg1655b1159
locus tag w3110JW1145
gene name k12mcrA
locus namemcrA
synonyms of locus namerglA

SCOPno information
pfam idPF01844
pfam domainHNH endonuclease
TIGRFAMno information

swissprot nameMCRA_ECOLI
description5-methylcytosine-specific restriction enzyme A (EC 3.1.21.-)|(EcoKMcrA).
seq length277
fastaseq

GOno information

gene product descriptione14 prophage; 5-methylcytosine-specific restriction endonuclease B
comment gene product description
evidenceE
contextcryptic prophage e14
gene product descPhage/IS in common(including 15 pseudogenes)
cell locationCytoplasmic
featuresCDS

functional category codeV
functional categoryDefense mechanisms

reference #1McrA and McrB restriction phenotypes of some E. coli strains and implications for gene cloning.

Raleigh E., Murray N., Revel H., Blumenthal R., Westaway D., Reith A., Rigby P., Elhai J., Hanahan D. (Nucleic Acids Res. 1988 Feb 25; 16(4):1563-75)
reference #2Genetic and physical mapping of the mcrA (rglA) and mcrB (rglB) loci of Escherichia coli K-12.

Raleigh E., Trimarchi R., Revel H. (Genetics. 1989 Jun; 122(2):279-96)
reference #3Cloning and structural characterization of the mcrA locus of Escherichia coli.

Hiom K., Sedgwick S. (J Bacteriol. 1991 Nov; 173(22):7368-73)

phylogenetic profile
 
1 1 1 1 1 1 1 1 1 1 1 54 1 1 1 1 1 1 1 1
1 1 1 1 1 1 1 1 1 1 1 63 1 1 1 1 1 1 1 1
1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
1 1 1 1 1 1 1 50 121 1 1 1 1 1 1 1 1 55 1 1
1 1 1 1 1 1 1 1 1 1 54 1 1 1 1 1 1 1 1 1
1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 51
1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1