Gene Details


gene name: thrB


locus tag k12ECK0003 Crenarchaeota Euryarchaeota Nanoarcheota Alphaproteobacteria Betaproteobacteria Gammaproteobacteria Deltaproteobacteria Epsilonproteobacteria Cyanobacteria Actinobacteridae Firmicutes Spirochaetes others Protist Microsporidia Fungi Metazoa Plantae
information on phylogenetic profile
locus tag mg1655b0003
locus tag w3110JW0002
gene name k12thrB
locus namethrB
synonyms of locus name

scop id54211; 55060
superfamilyRibosomal protein S5 domain 2-like; GHMP Kinase
pfam idPF00288
pfam domainGHMP kinases putative ATP-binding protei
tigrfam idTIGR00191
namethrB
functionhomoserine kinase

swissprot nameKHSE_ECOLI
descriptionHomoserine kinase (EC 2.7.1.39) (HSK) (HK).
seq length310
fastaseq

go idGO:0005737; GO:0009088
go termcytoplasm; threonine biosynthesis

gene product descriptionhomoserine kinase
comment gene product description
evidenceE
context
gene product descEnzyme
cell locationCytoplasmic
featuresCDS

functional category codeE
functional categoryAmino acid transport and metabolism

reference #1Homoserine kinase from Escherichia coli K12.

Burr B., Walker J., Truffa-Bachi P., Cohen G. (Eur J Biochem. 1976 Mar 1; 62(3):519-26)
reference #2Nucleotide sequence of the thrB gene of E. coli, and its two adjacent regions; the thrAB and thrBC junctions.

Cossart P., Katinka M., Yaniv M. (Nucleic Acids Res. 1981 Jan 24; 9(2):339-47)

phylogenetic profile
 
83 85 92 80 1 114 1 108 105 121 1 1 72 105 99 77 96 97 1 55
76 70 69 75 71 76 71 71 55 80 95 95 97 51 51 1 1 1 1 50
50 50 52 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 84
120 96 90 90 105 145 127 1 1 50 1 73 68 62 63 72 75 82 75 94
76 92 101 58 89 73 1 73 70 67 65 63 65 65 1 1 1 1 1 1
1 1 92 1 82 81 83 81 83 82 83 89 85 85 1 1 1 1 1 102
1 1 330 359 379 380 1 487 598 599 599 368 1 1 366 1 366 444 1 1
1 561 561 561 324 598 598 430 428 420 1 119 120 127 127 476 476 476 104 1
1 1 1 1 1 1 1 118 103 1 1 1 1 90 80 1 60 1 1 60
1 66 80 1 1 1 70 72 272 1 1 1 1 1 1 1 1 1 1