gene name: surA
| locus tag k12 | ECK0054 | information on phylogenetic profile |
|---|---|---|
| locus tag mg1655 | b0053 | |
| locus tag w3110 | JW0052 | |
| gene name k12 | surA | |
| locus name | surA | |
| synonyms of locus name |
| scop id | 54534 |
|---|---|
| superfamily | FKBP-like |
| pfam id | PF00639 |
| pfam domain | PPIC-type PPIASE domain |
| TIGRFAM | no information |
| swissprot name | SURA_ECOLI |
|---|---|
| description | Chaperone surA precursor (Peptidyl-prolyl cis-trans isomerase surA)|(EC 5.2.1.8) (PPIase) (Rotamase C) (Survival protein surA). |
| seq length | 428 |
| fastaseq |
| go id | GO:0009279; GO:0009279; GO:0006457 |
|---|---|
| go term | external outer membrane (sensu Gram-negative Bacteria); outer membrane (sensu Gram-negative Bacteria); protein folding |
| gene product description | peptidyl-prolyl cis-trans isomerase (PPIase) |
|---|---|
| comment gene product description | |
| evidence | E |
| context | |
| gene product desc | Enzyme |
| cell location | Periplasmic |
| features | CDS |
| functional category code | O |
|---|---|
| functional category | Posttranslational modification, protein turnover, chaperones |
| reference #1 | The SurA periplasmic PPIase lacking its parvulin domains functions in vivo and has chaperone activity. Behrens S., Maier R., de Cock H., Schmid F., Gross C. (EMBO J. 2001 Jan 15; 20(1-2):285-94) |
|---|---|
| reference #2 | Interaction of the periplasmic peptidylprolyl cis-trans isomerase SurA with model peptides. The N-terminal region of SurA id essential and sufficient for peptide binding. Webb H., Ruddock L., Marchant R., Jonas K., Klappa P. (J Biol Chem. 2001 Dec 7; 276(49):45622-7) |
| reference #3 | New components of protein folding in extracytoplasmic compartments of Escherichia coli SurA, FkpA and Skp/OmpH. Missiakas D., Betton J., Raina S. (Mol Microbiol. 1996 Aug; 21(4):871-84) |
| reference #4 | surA, an Escherichia coli gene essential for survival in stationary phase. Tormo A., Almirón M., Kolter R. (J Bacteriol. 1990 Aug; 172(8):4339-47) |
| reference #5 | Overlap between pdxA and ksgA in the complex pdxA-ksgA-apaG-apaH operon of Escherichia coli K-12. Roa B., Connolly D., Winkler M. (J Bacteriol. 1989 Sep; 171(9):4767-77) |
| reference #6 | SurA assists the folding of Escherichia coli outer membrane proteins. Lazar S., Kolter R. (J Bacteriol. 1996 Mar; 178(6):1770-3) |
| reference #7 | Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12. Link A., Robison K., Church G. (Electrophoresis. 1997 Aug; 18(8):1259-313) |
| reference #8 | Protein identification with N and C-terminal sequence tags in proteome projects. Wilkins M., Gasteiger E., Tonella L., Ou K., Tyler M., Sanchez J., Gooley A., Walsh B., Bairoch A., Appel R., Williams K., Hochstrasser D. (J Mol Biol. 1998 May 8; 278(3):599-608) |
| phylogenetic profile |
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