gene name: pdxA
| locus tag k12 | ECK0053 | information on phylogenetic profile |
|---|---|---|
| locus tag mg1655 | b0052 | |
| locus tag w3110 | JW0051 | |
| gene name k12 | pdxA | |
| locus name | pdxA | |
| synonyms of locus name |
| SCOP | no information |
|---|---|
| pfam id | PF04166 |
| pfam domain | Pyridoxal phosphate biosynthetic protein Pdx |
| tigrfam id | TIGR00557 |
| name | pdxA |
| function | 4-hydroxythreonine-4-phosphate dehydro |
| swissprot name | PDXA_ECOLI |
|---|---|
| description | 4-hydroxythreonine-4-phosphate dehydrogenase (EC 1.1.1.262) (4-|(phosphohydroxy)-L-threonine dehydrogenase). |
| seq length | 329 |
| fastaseq |
| go id | GO:0005737; GO:0008615 |
|---|---|
| go term | cytoplasm; pyridoxine biosynthesis |
| gene product description | 4-hydroxy-L-threonine phosphate dehydrogenase, NAD-dependent |
|---|---|
| comment gene product description | |
| evidence | E |
| context | |
| gene product desc | Enzyme |
| cell location | Cytoplasmic |
| features | CDS |
| functional category code | H |
|---|---|
| functional category | Coenzyme transport and metabolism |
| reference #1 | Crystal structure of Escherichia coli PdxA, an enzyme involved in the pyridoxal phosphate biosynthesis pathway. Sivaraman J., Li Y., Banks J., Cane D., Matte A., Cygler M. (J Biol Chem. 2003 Oct 31; 278(44):43682-90) |
|---|---|
| reference #2 | Overlap between pdxA and ksgA in the complex pdxA-ksgA-apaG-apaH operon of Escherichia coli K-12. Roa B., Connolly D., Winkler M. (J Bacteriol. 1989 Sep; 171(9):4767-77) |
| reference #3 | Vitamin B6 biosynthesis: formation of pyridoxine 5'-phosphate from 4-(phosphohydroxy)-L-threonine and 1-deoxy-D-xylulose-5-phosphate by PdxA and PdxJ protein. Laber B., Maurer W., Scharf S., Stepusin K., Schmidt F. (FEBS Lett. 1999 Apr 16; 449(1):45-8) |
| phylogenetic profile |
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