Gene Details


gene name: nhaA


locus tag k12ECK0020 Crenarchaeota Euryarchaeota Nanoarcheota Alphaproteobacteria Betaproteobacteria Gammaproteobacteria Deltaproteobacteria Epsilonproteobacteria Cyanobacteria Actinobacteridae Firmicutes Spirochaetes others Protist Microsporidia Fungi Metazoa Plantae
information on phylogenetic profile
locus tag mg1655b0019
locus tag w3110JW0018
gene name k12nhaA
locus namenhaA
synonyms of locus nameant, antA, hyc

SCOPno information
pfam idPF06965
pfam domainNa+/H+ antiporter
tigrfam idTIGR00773
nameNhaA
functionNa+/H+ antiporter NhaA

swissprot nameNHAA_ECOLI
descriptionNa(+)/H(+) antiporter 1 (Sodium/proton antiporter 1).
seq length388
fastaseq

go idGO:0009274; GO:0019866; GO:0009268
go termcell wall (sensu Bacteria); inner membrane; response to pH

gene product descriptionsodium-proton antiporter
comment gene product description
evidenceE
context
gene product descTransporter
cell locationIntegral Membrane Protein
featuresCDS

functional category codeP
functional categoryInorganic ion transport and metabolism

reference #1Overproduction and purification of a functional Na+/H+ antiporter coded by nhaA (ant) from Escherichia coli.

Taglicht D., Padan E., Schuldiner S. (J Biol Chem. 1991 Jun 15; 266(17):11289-94)
reference #2Cloning, sequencing, and expression of the nhaB gene, encoding a Na+/H+ antiporter in Escherichia coli.

Pinner E., Padan E., Schuldiner S. (J Biol Chem. 1992 Jun 5; 267(16):11064-8)
reference #3Physiological role of nhaB, a specific Na+/H+ antiporter in Escherichia coli.

Pinner E., Kotler Y., Padan E., Schuldiner S. (J Biol Chem. 1993 Jan 25; 268(3):1729-34)

phylogenetic profile
 
1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 158
1 1 1 1 1 1 1 1 191 178 188 192 1 139 139 1 225 218 1 251
257 271 251 1 77 1 1 206 1 285 285 1 1 1 1 1 1 1 1 1
1 1 1 1 1 1 1 1 292 1 91 267 209 231 230 236 1 1 1 1
1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
1 1 1 1 1 1 1 357 607 610 608 316 251 1 309 1 333 353 1 315
290 582 582 582 363 610 610 336 332 326 200 1 1 1 1 387 387 387 1 229
235 1 1 1 1 1 1 1 1 1 1 233 208 1 1 1 1 1 1 1
1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1