Gene Details


gene name: mreB


locus tag k12ECK3239 Crenarchaeota Euryarchaeota Nanoarcheota Alphaproteobacteria Betaproteobacteria Gammaproteobacteria Deltaproteobacteria Epsilonproteobacteria Cyanobacteria Actinobacteridae Firmicutes Spirochaetes others Protist Microsporidia Fungi Metazoa Plantae
information on phylogenetic profile
locus tag mg1655b3251
locus tag w3110JW3220
gene name k12mreB
locus namemreB
synonyms of locus nameenvB, mon, rodY

scop id53067
superfamilyActin-like ATPase domain
pfam idPF06723
pfam domainMreB/Mbl protein
tigrfam idTIGR00904
namemreB
functioncell shape determining protein, MreB/M

swissprot nameMREB_ECOLI
descriptionRod shape-determining protein mreB.
seq length347
fastaseq

go idGO:0042493
go termresponse to drug

gene product descriptioncell wall structural complex MreBCD, actin-like component MreB
comment gene product descriptioninteracts with MreC -!- actin homologue -!- predicted involvement in lateral cell wall synthesis
evidenceE
context
gene product descStructural component
cell locationCytoplasmic
featuresCDS

functional category codeD
functional categoryCell cycle control, cell division, chromosome partitioning

reference #1Dysfunctional MreB inhibits chromosome segregation in Escherichia coli.

Kruse T., Møller-Jensen J., Løbner-Olesen A., Gerdes K. (EMBO J. 2003 Oct 1; 22(19):5283-92)
reference #2A dynamic bacterial cytoskeleton.

Carballido-López R., Errington J. (Trends Cell Biol. 2003 Nov; 13(11):577-83)
reference #3Bacterial mitotic machineries.

Gerdes K., Møller-Jensen J., Ebersbach G., Kruse T., Nordström K. (Cell. 2004 Feb 6; 116(3):359-66)
reference #4New mre genes mreC and mreD, responsible for formation of the rod shape of Escherichia coli cells.

Wachi M., Doi M., Okada Y., Matsuhashi M. (J Bacteriol. 1989 Dec; 171(12):6511-6)
reference #5Determinations of the DNA sequence of the mreB gene and of the gene products of the mre region that function in formation of the rod shape of Escherichia coli cells.

Doi M., Wachi M., Ishino F., Tomioka S., Ito M., Sakagami Y., Suzuki A., Matsuhashi M. (J Bacteriol. 1988 Oct; 170(10):4619-24)
reference #6Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12.

Link A., Robison K., Church G. (Electrophoresis. 1997 Aug; 18(8):1259-313)
reference #7Determinations of the DNA sequence of the mreB gene and of the gene products of the mre region that function in formation of the rod shape of Escherichia coli cells.

Doi M., Wachi M., Ishino F., Tomioka S., Ito M., Sakagami Y., Suzuki A., Matsuhashi M. (J Bacteriol. 1988 Oct; 170(10):4619-24)

phylogenetic profile
 
1 1 1 1 212 65 62 50 1 1 1 57 63 62 214 1 64 1 1 59
1 385 68 68 381 380 57 67 59 68 58 65 65 67 64 55 59 376 57 56
56 57 57 399 56 391 392 389 55 488 488 488 492 492 490 53 56 473 495 58
332 334 345 362 368 333 334 418 423 395 423 352 350 363 379 362 58 67 67 375
374 328 62 339 372 371 371 368 371 387 390 375 377 67 381 380 381 61 373 61
61 61 61 58 65 68 58 70 62 64 62 62 61 55 61 62 62 355 67 65
67 667 654 710 710 710 551 540 540 536 539 543 667 667 553 662 54 541 545 544
61 65 602 673 673 673 610 710 711 616 624 624 627 453 539 539 536 536 65 376
359 359 359 357 355 357 293 358 333 344 331 59 267 269 264 340 379 328 379 325
65 63 62 58 62 60 69 55 67 67 60 57 60 62 57 57 60 61 71