Gene Details


gene name: mog


locus tag k12ECK0009 Crenarchaeota Euryarchaeota Nanoarcheota Alphaproteobacteria Betaproteobacteria Gammaproteobacteria Deltaproteobacteria Epsilonproteobacteria Cyanobacteria Actinobacteridae Firmicutes Spirochaetes others Protist Microsporidia Fungi Metazoa Plantae
information on phylogenetic profile
locus tag mg1655b0009
locus tag w3110JW0008
gene name k12mog
locus namemog
synonyms of locus namebisD, chlG, mogA, yaaG

scop id53218
superfamilyMolybdenum cofactor biosynthesis proteins
pfam idPF00994
pfam domainProbable molybdopterin binding domain
tigrfam idTIGR00177
namemolyb_syn
functionmolybdenum cofactor synthesis do

swissprot nameMOG_ECOLI
descriptionMolybdopterin biosynthesis mog protein.
seq length195
fastaseq

go idGO:0005737; GO:0006777
go termcytoplasm; Mo-molybdopterin cofactor biosynthesis

gene product descriptionpredicted molybdochelatase
comment gene product description
evidenceC
context
gene product descFactor, predicted
cell locationCytoplasmic
featuresCDS

functional category codeH
functional categoryCoenzyme transport and metabolism

reference #1Crystal structure of the gephyrin-related molybdenum cofactor biosynthesis protein MogA from Escherichia coli.

Liu M., Wuebbens M., Rajagopalan K., Schindelin H. (J Biol Chem. 2000 Jan 21; 275(3):1814-22)
reference #2Biogenesis of molybdenum cofactors.

Hinton S., Dean D. (Crit Rev Microbiol. 1990; 17(3):169-88)
reference #3Proposed nomenclature for the genes involved in molybdenum metabolism in Escherichia coli and Salmonella typhimurium.

Shanmugam K., Stewart V., Gunsalus R., Boxer D., Cole J., Chippaux M., DeMoss J., Giordano G., Lin E., Rajagopalan K. (Mol Microbiol. 1992 Nov; 6(22):3452-4)
reference #4Molecular genetic analysis of the moa operon of Escherichia coli K-12 required for molybdenum cofactor biosynthesis.

Rivers S., McNairn E., Blasco F., Giordano G., Boxer D. (Mol Microbiol. 1993 Jun; 8(6):1071-81)
reference #5Molybdenum cofactor biosynthesis in Escherichia coli mod and mog mutants.

Joshi M., Johnson J., Rajagopalan K. (J Bacteriol. 1996 Jul; 178(14):4310-2)
reference #6The Drosophila molybdenum cofactor gene cinnamon is homologous to three Escherichia coli cofactor proteins and to the rat protein gephyrin.

Kamdar K., Shelton M., Finnerty V. (Genetics. 1994 Jul; 137(3):791-801)
reference #7Five open reading frames upstream of the dnaK gene of E. coli.

James R., Dean D., Debbage J. (DNA Seq. 1993; 3(5):327-32)

phylogenetic profile
 
64 62 53 1 54 57 71 61 60 56 67 62 1 61 67 71 1 1 1 1
55 57 64 1 79 1 79 79 78 70 84 80 51 1 1 67 1 1 54 177
177 1 65 51 1 1 1 63 1 264 264 263 268 270 279 1 1 1 256 64
198 1 1 1 50 1 1 1 90 87 120 183 178 178 180 198 60 62 61 58
53 50 104 94 1 109 1 1 1 55 58 58 58 58 1 1 1 1 1 1
1 1 1 1 62 64 64 64 64 1 1 1 1 1 1 1 1 1 1 1
1 64 1 1 1 1 1 338 382 384 384 313 1 1 302 53 305 334 62 58
60 355 348 355 193 384 384 53 52 51 1 57 55 1 1 347 347 347 195 1
1 1 1 1 1 1 1 50 61 1 1 60 1 1 109 1 1 1 1 1
1 1 1 1 64 1 1 1 90 52 73 82 93 93 1 88 85 1 1