Gene Details


gene name: malP


locus tag k12ECK3404 Crenarchaeota Euryarchaeota Nanoarcheota Alphaproteobacteria Betaproteobacteria Gammaproteobacteria Deltaproteobacteria Epsilonproteobacteria Cyanobacteria Actinobacteridae Firmicutes Spirochaetes others Protist Microsporidia Fungi Metazoa Plantae
information on phylogenetic profile
locus tag mg1655b3417
locus tag w3110JW5689
gene name k12malP
locus namemalP
synonyms of locus nameblu, malA

scop id53756
superfamilyUDP-Glycosyltransferase/glycogen phosphorylase
pfam idPF00343
pfam domainCarbohydrate phosphorylase
tigrfam idTIGR02093
nameP_ylase
functionglycogen/starch/alpha-glucan phosph

swissprot namePHSM_ECOLI
descriptionMaltodextrin phosphorylase (EC 2.4.1.1).
seq length796
fastaseq

go idGO:0016052; GO:0016052; GO:0000272
go termcarbohydrate catabolism; carb catab; polysaccharide catabolism

gene product descriptionmaltodextrin phosphorylase
comment gene product description
evidenceE
context
gene product descEnzyme
cell locationCytoplasmic
featuresCDS

COGno information

reference #1The crystal structure of the Escherichia coli maltodextrin phosphorylase-acarbose complex.

O'Reilly M., Watson K., Johnson L. (Biochemistry. 1999 Apr 27; 38(17):5337-45)
reference #2Phosphorylase recognition and phosphorolysis of its oligosaccharide substrate: answers to a long outstanding question.

Watson K., McCleverty C., Geremia S., Cottaz S., Driguez H., Johnson L. (EMBO J. 1999 Sep 1; 18(17):4619-32)
reference #3Molecular characterization of malQ, the structural gene for the Escherichia coli enzyme amylomaltase.

Pugsley A., Dubreuil C. (Mol Microbiol. 1988 Jul; 2(4):473-9)
reference #4Evolution of catalytic and regulatory sites in phosphorylases.

Palm D., Goerl R., Burger K. (Nature. 313(6002):500-2)
reference #5E. coli maltodextrin phosphorylase: primary structure and deletion mapping of the C-terminal site.

Palm D., Goerl R., Weidinger G., Zeier R., Fischer B., Schinzel R. (Z Naturforsch [C]. 1987 Apr; 42(4):394-400)
reference #6A DNA sequence containing the control sites for gene malT and for the malPQ operon.

Debarbouille M., Cossart P., Raibaud O. (Mol Gen Genet. 1982; 185(1):88-92)
reference #7Use of deletions created in vitro to map transcriptional regulatory signals in the malA region of Escherichia coli.

Raibaud O., Débarbouillé M., Schwartz M. (J Mol Biol. 1983 Jan 25; 163(3):395-408)
reference #8N-terminal sequences of Escherichia coli and potato phosphorylase.

Schiltz E., Palm D., Klein H. (FEBS Lett. 1980 Jan 1; 109(1):59-62)
reference #9The crystal structure of Escherichia coli maltodextrin phosphorylase provides an explanation for the activity without control in this basic archetype of a phosphorylase.

Watson K., Schinzel R., Palm D., Johnson L. (EMBO J. 1997 Jan 2; 16(1):1-14)
reference #10Membrane-bound phosphatases in Escherichia coli: sequence of the pgpA gene.

Icho T. (J Bacteriol. 1988 Nov; 170(11):5110-6)

phylogenetic profile
 
1 60 1 1 1 1 1 1 68 73 72 1 70 75 1 1 1 1 1 1
587 1 1 578 69 71 1 62 1 555 562 1 1 1 1 1 598 1 631 595
1 1 608 1 609 1 1 1 1 1 1 1 1 1 1 1 1 1 1 674
632 638 1 668 701 640 655 1 73 1 636 1 1 1 1 1 551 1 1 546
528 493 1 1 1 1 1 1 1 52 1 561 580 1 523 526 523 412 563 410
410 411 412 1 1 1 1 1 1 1 1 455 412 1 411 520 456 555 1 1
1 652 1003 1534 1537 1537 647 1 1 1 900 672 652 1158 622 1116 1 560 576 573
1 1 1 1404 1414 1404 646 1526 1526 795 788 798 1 1 1 1 1 1 598 492
600 600 600 584 593 595 1 1 1 1 562 1 60 58 57 1 1 1 1 608
557 562 549 583 574 556 1 603 655 650 633 635 620 619 1 570 587 531 1