Gene Details


gene name: lspA


locus tag k12ECK0028 Crenarchaeota Euryarchaeota Nanoarcheota Alphaproteobacteria Betaproteobacteria Gammaproteobacteria Deltaproteobacteria Epsilonproteobacteria Cyanobacteria Actinobacteridae Firmicutes Spirochaetes others Protist Microsporidia Fungi Metazoa Plantae
information on phylogenetic profile
locus tag mg1655b0027
locus tag w3110JW0025
gene name k12lspA
locus namelspA
synonyms of locus namedapB, ileS

SCOPno information
pfam idPF01252
pfam domainSignal peptidase (SPase) II
tigrfam idTIGR00077
namelspA
functionlipoprotein signal peptidase

swissprot nameLSPA_ECOLI
descriptionLipoprotein signal peptidase (EC 3.4.23.36) (Prolipoprotein signal|peptidase) (Signal peptidase II) (SPase II).
seq length164
fastaseq

go idGO:0009274; GO:0019866
go termcell wall (sensu Bacteria); inner membrane

gene product descriptionprolipoprotein signal peptidase (signal peptidase II)
comment gene product description
evidenceE
context
gene product descEnzyme
cell locationIntegral Membrane Protein
featuresCDS

functional category codeM; U
functional categoryCell wall/membrane/envelope biogenesis ; Intracellular trafficking, secretion, and vesicular transport

reference #1Membrane topology of Escherichia coli prolipoprotein signal peptidase (signal peptidase II).

Muñoa F., Miller K., Beers R., Graham M., Wu H. (J Biol Chem. 1991 Sep 15; 266(26):17667-72)
reference #2Nucleotide sequence of the lspA gene, the structural gene for lipoprotein signal peptidase of Escherichia coli.

Yu F., Yamada H., Daishima K., Mizushima S. (FEBS Lett. 1984 Jul 23; 173(1):264-8)

phylogenetic profile
 
1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
58 63 60 64 1 51 1 1 56 1 60 67 84 1 1 100 100 96 69 102
102 90 83 65 68 64 63 105 71 119 119 117 127 127 99 118 118 119 128 93
70 59 1 63 51 78 69 84 108 99 94 63 1 59 59 56 96 95 94 89
82 84 62 1 72 77 63 64 74 83 83 82 83 82 1 1 1 1 1 1
1 1 73 1 73 74 74 74 74 68 69 76 65 65 80 79 78 79 79 66
1 121 94 108 113 129 126 244 305 302 302 157 130 130 160 129 167 218 110 100
105 283 282 283 154 305 305 162 164 166 102 118 117 109 110 211 211 211 74 1
1 67 67 67 58 59 60 60 1 82 55 50 1 53 1 1 1 51 1 1
1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1