gene name: kefC
| locus tag k12 | ECK0048 | information on phylogenetic profile |
|---|---|---|
| locus tag mg1655 | b0047 | |
| locus tag w3110 | JW0046 | |
| gene name k12 | kefC | |
| locus name | kefC | |
| synonyms of locus name | trkC |
| scop id | 51735 |
|---|---|
| superfamily | NAD(P)-binding Rossmann-fold domains |
| pfam id | PF02254 |
| pfam domain | TrkA-N domain |
| tigrfam id | TIGR00932 |
| name | 2a37 |
| function | potassium efflux system protein |
| swissprot name | KEFC_ECOLI |
|---|---|
| description | Glutathione-regulated potassium-efflux system protein kefC (K(+)/H(+)|antiporter). |
| seq length | 620 |
| fastaseq |
| go id | GO:0009274; GO:0019866; GO:0015386 |
|---|---|
| go term | cell wall (sensu Bacteria); inner membrane; potassium:hydrogen antiporter activity |
| gene product description | potassium:proton antiporter |
|---|---|
| comment gene product description | glutathione-regulated |
| evidence | E |
| context | |
| gene product desc | Transporter |
| cell location | Integral Membrane Protein |
| features | CDS |
| functional category code | P |
|---|---|
| functional category | Inorganic ion transport and metabolism |
| reference #1 | Different foci for the regulation of the activity of the KefB and KefC glutathione-gated K+ efflux systems. Ness L., Booth I. (J Biol Chem. 1999 Apr 2; 274(14):9524-30) |
|---|---|
| reference #2 | Activation of potassium efflux from Escherichia coli by glutathione metabolites. Elmore M., Lamb A., Ritchie G., Douglas R., Munro A., Gajewska A., Booth I. (Mol Microbiol. 1990 Mar; 4(3):405-12) |
| reference #3 | The cloning and DNA sequence of the gene for the glutathione-regulated potassium-efflux system KefC of Escherichia coli. Munro A., Ritchie G., Lamb A., Douglas R., Booth I. (Mol Microbiol. 1991 Mar; 5(3):607-16) |
| reference #4 | The putative Na+/H+ antiporter (NapA) of Enterococcus hirae is homologous to the putative K+/H+ antiporter (KefC) of Escherichia coli. Reizer J., Reizer A., Saier M. (FEMS Microbiol Lett. 1992 Jul 1; 73(1-2):161-3) |
| reference #5 | Nucleotide sequence of the E coli gene coding for dihydrofolate reductase. Smith D., Calvo J. (Nucleic Acids Res. 1980 May 24; 8(10):2255-74) |
| phylogenetic profile |
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