gene name: fimE
| locus tag k12 | ECK4304 | information on phylogenetic profile |
|---|---|---|
| locus tag mg1655 | b4313 | |
| locus tag w3110 | JW4276 | |
| gene name k12 | fimE | |
| locus name | fimE | |
| synonyms of locus name | pilH, hyp |
| scop id | 56349 |
|---|---|
| superfamily | DNA breaking-rejoining enzymes |
| pfam id | PF00589 |
| pfam domain | Phage integrase family |
| TIGRFAM | no information |
| swissprot name | FIME_ECOLI |
|---|---|
| description | Type 1 fimbriae regulatory protein fimE. |
| seq length | 198 |
| fastaseq |
| go id | GO:0005737; GO:0009289; GO:0006310; GO:0009297 |
|---|---|
| go term | cytoplasm; fimbria; DNA recombination; fimbrial biogenesis |
| gene product description | tyrosine recombinase/inversion of on/off regulator of fimA |
|---|---|
| comment gene product description | catalyses inversion of the switch for fimA expression from the ON to the OFF phase |
| evidence | E |
| context | |
| gene product desc | Regulator |
| cell location | Cytoplasmic |
| features | CDS |
| functional category code | L |
|---|---|
| functional category | Replication, recombination and repair |
| reference #1 | Differential temperature modulation by H-NS of the fimB and fimE recombinase genes which control the orientation of the type 1 fimbrial phase switch. Olsen P., Schembri M., Gally D., Klemm P. (FEMS Microbiol Lett. 1998 May 1; 162(1):17-23) |
|---|---|
| reference #2 | Regulation of the phase switch controlling expression of type 1 fimbriae in Escherichia coli. Pallesen L., Madsen O., Klemm P. (Mol Microbiol. 1989 Jul; 3(7):925-31) |
| reference #3 | Type 1 fimbriation and fimE mutants of Escherichia coli K-12. Blomfield I., McClain M., Princ J., Calie P., Eisenstein B. (J Bacteriol. 1991 Sep; 173(17):5298-307) |
| reference #4 | Roles of fimB and fimE in site-specific DNA inversion associated with phase variation of type 1 fimbriae in Escherichia coli. McClain M., Blomfield I., Eisenstein B. (J Bacteriol. 1991 Sep; 173(17):5308-14) |
| reference #5 | Two regulatory fim genes, fimB and fimE, control the phase variation of type 1 fimbriae in Escherichia coli. Klemm P. (EMBO J. 1986 Jun; 5(6):1389-93) |
| phylogenetic profile |
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