Gene Details


gene name: fabZ


locus tag k12ECK0179 Crenarchaeota Euryarchaeota Nanoarcheota Alphaproteobacteria Betaproteobacteria Gammaproteobacteria Deltaproteobacteria Epsilonproteobacteria Cyanobacteria Actinobacteridae Firmicutes Spirochaetes others Protist Microsporidia Fungi Metazoa Plantae
information on phylogenetic profile
locus tag mg1655b0180
locus tag w3110JW0175
gene name k12fabZ
locus namefabZ
synonyms of locus namesefA, yaeA, sabA, sfhC

scop id54637
superfamilyThioesterase/thiol ester dehydrase-isomerase
pfam idPF03061
pfam domainThioesterase superfamily
tigrfam idTIGR01750
namefabZ
functionbeta-hydroxyacyl-(acyl-carrier-protein

swissprot nameFABZ_ECOLI
description(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.-)|((3R)-hydroxymyristoyl ACP dehydrase) (17 kDa actomyosin component).
seq length151
fastaseq

go idGO:0005737
go termcytoplasm

gene product description(3R)-hydroxymyristol acyl carrier protein dehydratase
comment gene product description
evidenceE
context
gene product descEnzyme
cell locationCytoplasmic
featuresCDS

functional category codeI
functional categoryLipid transport and metabolism

reference #1Septum formation-defective mutant of Escherichia coli.

Normark S., Norlander L., Grundström T., Bloom G., Boquet P., Frelat G. (J Bacteriol. 1976 Oct; 128(1):401-12)
reference #2Roles of the FabA and FabZ beta-hydroxyacyl-acyl carrier protein dehydratases in Escherichia coli fatty acid biosynthesis.

Heath R., Rock C. (J Biol Chem. 1996 Nov 1; 271(44):27795-801)

phylogenetic profile
 
1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
1 1 1 1 1 1 1 1 1 1 51 1 146 1 1 133 135 136 123 129
129 135 135 130 122 114 114 133 121 151 148 151 171 171 172 164 164 153 152 132
122 137 131 144 132 141 141 1 132 150 153 134 117 127 127 127 138 136 136 130
138 129 116 130 128 129 1 111 134 146 146 146 146 146 1 1 1 1 1 1
1 1 144 1 122 122 122 122 122 136 136 131 130 129 130 130 130 123 128 142
1 134 239 126 169 64 153 268 302 303 300 199 146 143 193 154 214 251 157 163
165 301 301 301 187 302 303 199 207 204 50 148 141 129 129 272 273 273 166 124
125 118 118 118 113 115 109 140 137 134 114 77 121 126 134 1 1 94 1 1
1 1 1 1 1 1 1 1 191 1 1 1 1 1 1 134 65 1 127