Gene Details


gene name: djlA


locus tag k12ECK0056 Crenarchaeota Euryarchaeota Nanoarcheota Alphaproteobacteria Betaproteobacteria Gammaproteobacteria Deltaproteobacteria Epsilonproteobacteria Cyanobacteria Actinobacteridae Firmicutes Spirochaetes others Protist Microsporidia Fungi Metazoa Plantae
information on phylogenetic profile
locus tag mg1655b0055
locus tag w3110JW0054
gene name k12djlA
locus namedjlA
synonyms of locus nameyabH

scop id46565
superfamilyChaperone J-domain
pfam idPF00226
pfam domainDnaJ domain
TIGRFAMno information

swissprot nameDJLA_ECOLI
descriptionDnaJ-like protein djlA.
seq length271
fastaseq

go idGO:0006457
go termprotein folding

gene product descriptionDnaJ-like protein, membrane anchored
comment gene product descriptionco-chaperone with DnaK
evidenceE
context
gene product descFactor
cell locationMembrane Anchored
featuresCDS

functional category codeO
functional categoryPosttranslational modification, protein turnover, chaperones

reference #1DjlA is a third DnaK co-chaperone of Escherichia coli, and DjlA-mediated induction of colanic acid capsule requires DjlA-DnaK interaction.

Genevaux P., Wawrzynow A., Zylicz M., Georgopoulos C., Kelley W. (J Biol Chem. 2001 Mar 16; 276(11):7906-12)
reference #2Positive control of the two-component RcsC/B signal transduction network by DjlA: a member of the DnaJ family of molecular chaperones in Escherichia coli.

Kelley W., Georgopoulos C. (Mol Microbiol. 1997 Sep; 25(5):913-31)
reference #3Point mutations in the transmembrane domain of DjlA, a membrane-linked DnaJ-like protein, abolish its function in promoting colanic acid production via the Rcs signal transduction pathway.

Clarke D., Holland I., Jacq A. (Mol Microbiol. 1997 Sep; 25(5):933-44)
reference #4Rates of DNA sequence evolution in experimental populations of Escherichia coli during 20,000 generations.

Lenski R., Winkworth C., Riley M. (J Mol Evol. 2003 Apr; 56(4):498-508)
reference #5A novel DnaJ-like protein in Escherichia coli inserts into the cytoplasmic membrane with a type III topology.

Clarke D., Jacq A., Holland I. (Mol Microbiol. 1996 Jun; 20(6):1273-86)
reference #6DjlA is a third DnaK co-chaperone of Escherichia coli, and DjlA-mediated induction of colanic acid capsule requires DjlA-DnaK interaction.

Genevaux P., Wawrzynow A., Zylicz M., Georgopoulos C., Kelley W. (J Biol Chem. 2001 Mar 16; 276(11):7906-12)

phylogenetic profile
 
1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 73 1 1 1 58
58 50 60 1 1 1 1 67 1 1 1 1 1 1 1 1 1 1 1 1
1 1 1 1 1 1 1 1 55 1 1 61 1 1 1 65 1 1 1 1
1 1 1 50 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
1 1 1 1 1 1 157 290 447 447 447 242 120 122 239 172 229 324 76 82
95 430 430 430 206 447 447 216 229 229 1 1 1 1 1 339 339 338 1 1
1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
1 1 1 1 1 1 1 1 52 1 1 1 1 1 1 1 1 1 1