Gene Details


gene name: der


locus tag k12ECK2507 Crenarchaeota Euryarchaeota Nanoarcheota Alphaproteobacteria Betaproteobacteria Gammaproteobacteria Deltaproteobacteria Epsilonproteobacteria Cyanobacteria Actinobacteridae Firmicutes Spirochaetes others Protist Microsporidia Fungi Metazoa Plantae
information on phylogenetic profile
locus tag mg1655b2511
locus tag w3110JW5403
gene name k12der
locus nameder
synonyms of locus nameengA, yfgK

scop id52540
superfamilyP-loop containing nucleotide triphosphate hydrolases
pfam idPF01926
pfam domainGTPase of unknown function
tigrfam idTIGR00231; TIGR00650
nameTIGR00231; TIGR00650
functionsmall GTP-binding prot domain; GTP-binding conserved hypothetical prot

swissprot nameENGA_ECOLI
descriptionGTP-binding protein engA (Double era-like domain protein).
seq length490
fastaseq

GOno information

gene product descriptionpredicted GTP-binding protein
comment gene product descriptionessential for growth -!- multicopy suppressor of ftsJ -!- depleted cells form filaments with defective chromosome segregation
evidenceC
context
gene product descFactor, predicted
cell locationCytoplasmic
featuresCDS

functional category codeR
functional categoryGeneral function prediction only

reference #1An essential GTPase, der, containing double GTP-binding domains from Escherichia coli and Thermotoga maritima.

Hwang J., Inouye M. (J Biol Chem. 2001 Aug 17; 276(33):31415-21)

phylogenetic profile
 
1 1 1 55 1 1 51 54 1 53 1 1 1 65 62 67 1 1 1 243
251 259 255 266 251 240 251 251 251 264 253 254 321 220 220 310 280 293 318 294
293 305 288 320 275 264 268 304 242 433 433 433 446 446 441 440 441 420 434 306
282 269 290 279 290 296 275 220 311 249 333 221 241 208 206 253 313 313 315 312
296 298 315 318 322 300 316 283 291 321 322 278 226 322 237 243 210 237 262 226
236 219 304 276 330 330 330 330 330 277 276 288 283 283 286 286 286 287 287 331
256 508 351 316 382 423 456 777 932 935 933 653 527 523 659 489 653 769 548 553
543 892 893 892 668 931 907 663 676 670 269 433 435 429 431 761 761 761 278 288
288 226 226 226 239 236 246 276 254 300 269 246 300 238 251 206 207 207 186 208
58 83 76 77 61 78 53 64 62 67 67 62 65 65 1 214 256 1 156