gene name: dapB
| locus tag k12 | ECK0032 | information on phylogenetic profile |
|---|---|---|
| locus tag mg1655 | b0031 | |
| locus tag w3110 | JW0029 | |
| gene name k12 | dapB | |
| locus name | dapB | |
| synonyms of locus name |
| scop id | 55347; 51735 |
|---|---|
| superfamily | Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; NAD(P)-binding Rossmann-fold domains |
| pfam id | PF01113; PF05173 |
| pfam domain | Dihydrodipicolinate reductase, N-terminus; Dihydrodipicolinate reductase, C-terminus |
| tigrfam id | TIGR00036 |
| name | dapB |
| function | dihydrodipicolinate reductase |
| swissprot name | DAPB_ECOLI |
|---|---|
| description | Dihydrodipicolinate reductase (EC 1.3.1.26) (DHPR). |
| seq length | 273 |
| fastaseq |
| go id | GO:0005737; GO:0009274; GO:0009089 |
|---|---|
| go term | cytoplasm; cell wall (sensu Bacteria); lysine biosynthesis via diaminopimelate |
| gene product description | dihydrodipicolinate reductase |
|---|---|
| comment gene product description | |
| evidence | E |
| context | |
| gene product desc | Enzyme |
| cell location | Cytoplasmic |
| features | CDS |
| functional category code | E |
|---|---|
| functional category | Amino acid transport and metabolism |
| reference #1 | Dihydrodipicolinic acid reductase. Tamir H., Gilvarg C. (J Biol Chem. 1974 May 25; 249(10):3034-40) |
|---|---|
| reference #2 | Nucleotide sequence and expression of the Escherichia coli dapB gene. Bouvier J., Richaud C., Richaud F., Patte J., Stragier P. (J Biol Chem. 1984 Dec 10; 259(23):14829-34) |
| reference #3 | Multiple regulatory signals in the control region of the Escherichia coli carAB operon. Bouvier J., Patte J., Stragier P. (Proc Natl Acad Sci U S A. 1984 Jul; 81(13):4139-43) |
| reference #4 | Three-dimensional structure of Escherichia coli dihydrodipicolinate reductase. Scapin G., Blanchard J., Sacchettini J. (Biochemistry. 1995 Mar 21; 34(11):3502-12) |
| reference #5 | Three-dimensional structure of Escherichia coli dihydrodipicolinate reductase in complex with NADH and the inhibitor 2,6-pyridinedicarboxylate. Scapin G., Reddy S., Zheng R., Blanchard J. (Biochemistry. 1997 Dec 9; 36(49):15081-8) |
| phylogenetic profile |
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