Gene Details


gene name: caiT


locus tag k12ECK0041 Crenarchaeota Euryarchaeota Nanoarcheota Alphaproteobacteria Betaproteobacteria Gammaproteobacteria Deltaproteobacteria Epsilonproteobacteria Cyanobacteria Actinobacteridae Firmicutes Spirochaetes others Protist Microsporidia Fungi Metazoa Plantae
information on phylogenetic profile
locus tag mg1655b0040
locus tag w3110JW0039
gene name k12caiT
locus namecaiT
synonyms of locus nameyaaT, yaaP

SCOPno information
pfam idPF02028
pfam domainBCCT family transporter
tigrfam idTIGR00842
namebcct
functioncholine/carnitine/betaine transport

swissprot nameCAIT_ECOLI
descriptionL-carnitine/gamma-butyrobetaine antiporter.
seq length504
fastaseq

go idGO:0009274; GO:0019866; GO:0016052; GO:0016052
go termcell wall (sensu Bacteria); inner membrane; carbohydrate catabolism; carb catab

gene product descriptionpredicted transporter
comment gene product description
evidenceC
context
gene product descTransporter, predicted
cell locationIntegral Membrane Protein
featuresCDS

functional category codeM
functional categoryCell wall/membrane/envelope biogenesis

reference #1CaiT of Escherichia coli, a new transporter catalyzing L-carnitine/gamma -butyrobetaine exchange.

Jung H., Buchholz M., Clausen J., Nietschke M., Revermann A., Schmid R., Jung K. (J Biol Chem. 2002 Oct 18; 277(42):39251-8)
reference #2Regulation of the carnitine pathway in Escherichia coli: investigation of the cai-fix divergent promoter region.

Buchet A., Eichler K., Mandrand-Berthelot M. (J Bacteriol. 1998 May; 180(10):2599-608)
reference #3A possible role of ProP, ProU and CaiT in osmoprotection of Escherichia coli by carnitine.

Verheul A., Wouters J., Rombouts F., Abee T. (J Appl Microbiol. 1998 Dec; 85(6):1036-46)
reference #4Molecular characterization of the cai operon necessary for carnitine metabolism in Escherichia coli.

Eichler K., Bourgis F., Buchet A., Kleber H., Mandrand-Berthelot M. (Mol Microbiol. 1994 Sep; 13(5):775-86)

phylogenetic profile
 
1 1 1 1 1 142 1 1 1 1 1 1 1 1 1 1 1 1 1 1
177 181 176 1 153 1 153 153 197 1 1 178 1 1 1 1 1 1 1 1
1 1 1 1 1 1 1 181 1 171 171 171 160 160 188 160 154 1 1 1
1 1 1 1 151 1 1 1 239 1 1 1 1 1 1 192 206 200 200 197
200 201 1 1 1 1 1 207 1 203 204 204 204 204 1 1 1 1 1 1
1 1 254 1 211 211 211 211 211 172 79 1 1 1 1 1 1 1 1 1
1 187 1 1 1 1 63 151 993 986 988 154 1 1 137 1 150 1 176 182
176 958 965 958 1 990 990 170 171 270 1 145 157 1 1 229 229 229 1 1
1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 191 168 1
1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1