Gene Details


gene name: caiD


locus tag k12ECK0037 Crenarchaeota Euryarchaeota Nanoarcheota Alphaproteobacteria Betaproteobacteria Gammaproteobacteria Deltaproteobacteria Epsilonproteobacteria Cyanobacteria Actinobacteridae Firmicutes Spirochaetes others Protist Microsporidia Fungi Metazoa Plantae
information on phylogenetic profile
locus tag mg1655b0036
locus tag w3110JW0035
gene name k12caiD
locus namecaiD
synonyms of locus nameyaaL

scop id52096
superfamilyClpP/crotonase
pfam idPF00378
pfam domainEnoyl-CoA hydratase/isomerase family
TIGRFAMno information

swissprot nameCAID_ECOLI
descriptionCarnitinyl-CoA dehydratase (EC 4.2.1.-) (Crotonobetainyl-CoA|hydratase).
seq length260
fastaseq

go idGO:0009310; GO:0042413
go termamine catabolism; carnitine catabolism

gene product descriptioncrotonobetainyl CoA hydratase
comment gene product description
evidenceE
context
gene product descEnzyme
cell locationCytoplasmic
featuresCDS

functional category codeI
functional categoryLipid transport and metabolism

reference #1Involvement of coenzyme A esters and two new enzymes, an enoyl-CoA hydratase and a CoA-transferase, in the hydration of crotonobetaine to L-carnitine by Escherichia coli.

Elssner T., Engemann C., Baumgart K., Kleber H. (Biochemistry. 2001 Sep 18; 40(37):11140-8)
reference #2Bacterial carnitine metabolism.

Kleber H. (FEMS Microbiol Lett. 1997 Feb 1; 147(1):1-9)
reference #3Molecular characterization of the cai operon necessary for carnitine metabolism in Escherichia coli.

Eichler K., Bourgis F., Buchet A., Kleber H., Mandrand-Berthelot M. (Mol Microbiol. 1994 Sep; 13(5):775-86)

phylogenetic profile
 
115 103 119 135 144 99 1 1 1 1 1 1 75 1 1 1 84 86 1 1
70 117 58 78 130 106 132 133 180 53 167 114 131 1 1 134 1 1 164 117
119 122 239 164 1 1 1 246 1 152 147 144 119 119 114 1 1 1 115 77
67 62 76 71 77 83 82 134 84 1 122 1 1 1 1 1 131 129 131 131
115 109 132 137 132 80 1 1 75 85 85 85 85 85 1 1 1 1 1 1
1 1 114 1 85 85 84 85 84 63 63 74 83 82 67 67 68 68 68 134
1 162 1 1 1 1 67 75 551 551 551 79 123 123 78 1 84 79 117 134
108 455 458 455 107 553 553 70 114 127 1 117 113 1 1 78 78 78 1 87
84 1 1 1 1 1 1 80 128 106 83 61 113 1 109 1 99 1 1 99
51 1 1 50 120 50 1 110 118 122 118 110 111 112 1 100 107 1 52