Gene Details


gene name: ampH


locus tag k12ECK0371 Crenarchaeota Euryarchaeota Nanoarcheota Alphaproteobacteria Betaproteobacteria Gammaproteobacteria Deltaproteobacteria Epsilonproteobacteria Cyanobacteria Actinobacteridae Firmicutes Spirochaetes others Protist Microsporidia Fungi Metazoa Plantae
information on phylogenetic profile
locus tag mg1655b0376
locus tag w3110JW5052
gene name k12ampH
locus nameampH
synonyms of locus nameyaiH

scop id56601
superfamilybeta-Lactamase/D-ala carboxypeptidase
pfam idPF00144
pfam domainBeta-lactamase
TIGRFAMno information

swissprot nameAMPH_ECOLI
descriptionPenicillin-binding protein ampH.
seq length385
fastaseq

go idGO:0042493
go termresponse to drug

gene product descriptionbeta-lactamase/D-alanine carboxypeptidase
comment gene product descriptionpenicillin-binding protein (PBP)
evidenceE
context
gene product descEnzyme
cell locationPeriplasmic
featuresCDS

functional category codeV
functional categoryDefense mechanisms

reference #1AmpC and AmpH, proteins related to the class C beta-lactamases, bind penicillin and contribute to the normal morphology of Escherichia coli.

Henderson T., Young K., Denome S., Elf P. (J Bacteriol. 1997 Oct; 179(19):6112-21)
reference #2Detection of new genes in a bacterial genome using Markov models for three gene classes.

Borodovsky M., McIninch J., Koonin E., Rudd K., Médigue C., Danchin A. (Nucleic Acids Res. 1995 Sep 11; 23(17):3554-62)

phylogenetic profile
 
53 58 1 1 1 1 1 1 1 1 68 1 1 54 1 60 1 1 1 1
1 58 1 1 65 1 62 65 62 1 70 66 70 1 1 1 1 1 69 1
1 99 71 66 62 60 60 60 1 1 1 1 1 1 331 1 1 1 1 62
64 1 1 1 1 53 1 1 1 1 60 1 1 1 1 1 70 65 65 71
64 63 61 1 1 50 1 55 1 64 65 65 65 65 1 1 1 1 1 1
1 1 73 1 52 57 54 55 54 53 52 56 1 1 1 1 1 1 1 60
1 1 1 1 1 1 1 1 725 730 729 1 73 71 1 1 1 369 58 61
53 676 660 676 50 725 725 1 1 1 1 67 63 60 60 431 431 431 1 67
1 1 1 1 1 1 1 59 61 1 1 85 1 1 62 1 1 1 1 1
1 1 1 1 1 1 1 1 1 50 1 1 1 53 1 1 1 1 1