gene name: adhE
| locus tag k12 | ECK1235 | information on phylogenetic profile |
|---|---|---|
| locus tag mg1655 | b1241 | |
| locus tag w3110 | JW1228 | |
| gene name k12 | adhE | |
| locus name | adhE | |
| synonyms of locus name | adhC, ana |
| scop id | 53720; 56796 |
|---|---|
| superfamily | ALDH-like; Dehydroquinate synthase-like |
| pfam id | PF00465 |
| pfam domain | Iron-containing alcohol dehydrogenase |
| TIGRFAM | no information |
| swissprot name | ADHE_ECOLI |
|---|---|
| description | Aldehyde-alcohol dehydrogenase [Includes: Alcohol dehydrogenase|(EC 1.1.1.1) (ADH); Acetaldehyde dehydrogenase [acetylating]|(EC 1.2.1.10) (ACDH); Pyruvate-formate-lyase deactivase (PFL|deactivase)]. |
| seq length | 890 |
| fastaseq |
| go id | GO:0006113 |
|---|---|
| go term | fermentation |
| gene product description | fused acetaldehyde-CoA dehydrogenase; iron-dependent alcohol dehydrogenase; pyruvate-formate lyase deactivase |
|---|---|
| comment gene product description | |
| evidence | E |
| context | |
| gene product desc | Enzyme |
| cell location | Cytoplasmic |
| features | CDS |
| functional category code | C |
|---|---|
| functional category | Energy production and conversion |
| reference #1 | Novel antioxidant role of alcohol dehydrogenase E from Escherichia coli. Echave P., Tamarit J., Cabiscol E., Ros J. (J Biol Chem. 2003 Aug 8; 278(32):30193-8) |
|---|---|
| reference #2 | Coenzyme A-linked aldehyde dehydrogenase from Escherichia coli. I. Partial purification, properties, and kinetic studies of the enzyme. Rudolph F., Purich D., Fromm H. (J Biol Chem. 1968 Nov 10; 243(21):5539-45) |
| reference #3 | Escherichia coli derivatives lacking both alcohol dehydrogenase and phosphotransacetylase grow anaerobically by lactate fermentation. Gupta S., Clark D. (J Bacteriol. 1989 Jul; 171(7):3650-5) |
| reference #4 | Pyruvate-formate-lyase-deactivase and acetyl-CoA reductase activities of Escherichia coli reside on a polymeric protein particle encoded by adhE. Kessler D., Leibrecht I., Knappe J. (FEBS Lett. 1991 Apr 9; 281(1-2):59-63) |
| phylogenetic profile |
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